What are the most important criteria for selecting Vitamin K2 MK7?

Top 5 Criteria for choosing a Vitamin K2 Product

Since the role of Vitamin K2 is emerging, numerous vitamin K2 products are on the market. However, it’s not always clear which products are high quality. This guide covers appropriate vitamin K2 supplements and choosing a safe and high-quality product.

What are the most important criteria for selecting Vitamin K2 MK7?

Is it natural fermented vitamin K2 MK7?

There are two vitamin k2s that are currently available on the market; synthetic vitamin K2 and natural fermented vitamin K2.

Since synthetic vitamin K2 uses toxic organic solvents and chemical catalysts, it is likely to remain in the final product due to difficulty in complete removal.

On the other hand, fermentation is a natural process carried out similarly to how yeast is used to make bread or how other microorganisms are used to obtain fermented foods such as yogurt and natto. This process makes fermented natural Vitamin k2 very safe from hazardous substances.

Check whether it meets USP standards

USP standards for vitamin K2 demonstrate identity, strength, purity, and quality, requiring a minimum of 96% MK-7.

According to studies from Molecules, the higher purity profile of vitamin K2 as MK-7 is correlated with enhanced stability, meaning that impurities are removed during the manufacturing process and therefore enhance the stability of a product (Orlando P et al., 2019).

To assure the safety and stability of Vitamin k2 product, it is essential to check whether it meets USP standards and uses ultra-high purity profile vitamin K2.

Does it guarantee trans-type 99.9% or higher?

MK-7 is divided into trans-type and cis-type, of which only trans-type is bioactive in our body.
Therefore, for vitamin K2 to work effectively in the body, it is necessary to take trans-type MK7.

Is it safe from storage stability when mixed with calcium and magnesium?

Vitamin K2 supplements are often manufactured by mixing them with alkaline minerals such as calcium and magnesium due to their role in controlling the calcium metabolism of vitamin K2.

However, vitamin K2 decomposes with alkaline minerals and its vitamin K2 content can get decreased. Using microencapsulation technology is critical to use a product that protects its vitamin k2 material from alkaline minerals such as calcium and magnesium.

Can it be used for water-soluble beverages?

Vitamin K2 is a fat-soluble ingredient that is not soluble in water. In order to have vitamin K2 used in various dosage forms like milk, yogurt, jelly, and beverages, it is essential to use vitamin K2 that can be dissolved well in aqueous solutions through micro-sized emulsification technology.

Reference | Orlando P, Silvestri S, Marcheggiani F, Cirilli I, Tiano L. Menaquinone 7 Stability of Formulations and Its Relationship with Purity Profile. Molecules. 2019;24(5):829.

Writing date: 2022-08-19