Health Benefits of Vitamin K2
Promoting Cardiovascular Health with Vitamin K2
Water-Soluble Vitamin K2: MediQ7 AquaSolvation Technology
Vitamin K2 plays a critical role in improving cardiovascular health, Activated MGP can improve cardiovascular disease by inhibiting calcium accumulation in blood vessels of arteries. Thus, vitamin k2 prevents artery wall calcification, CVD, and stroke. Vascular calcification causes cardiovascular diseases such as arteriosclerosis, vascular stiffness, heart disease, and myocardial infarction.
The Calcium Paradox
Calcium is vital for building strong bones and teeth. However, excessive calcium supplements have been linked to an increased risk of vascular calcification, where calcium deposits form in the blood vessels. This phenomenon, known as the Calcium Paradox, can lead to serious cardiovascular diseases such as arteriosclerosis, vascular stiffness, heart disease, and myocardial infarction. Essentially, the calcium intended for bones ends up accumulating in the blood vessels, causing cardiovascular diseases.
Vitamin K2 and MGP protein
Vitamin K2 addresses the Calcium Paradox by activating MGP, which inhibits the deposition of calcium on arterial walls. Adequate intake of Vitamin K2 significantly reduces the risk of vascular calcification and arterial stiffening. Conversely, a deficiency in Vitamin K2 impairs MGP activation, increasing the risk of cardiovascular diseases.
Clinical Evidence about Vitamin K2 and Cardiovascular Health
1. Meta-Analysis on Calcium Supplements and Cardiovascular Events
Several studies have investigated the importance of Vitamin K2 for cardiovascular benefits.
[Bolland, M. J., Avenell, A., Baron, J. A., Grey, A., MacLennan, G. S., Gamble, G. D., & Reid, I. R. (2010). "Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis.” BMJ, 341, c3691.]
2. The Rotterdam Study
A notable study conducted in Rotterdam in 2004 involved 4,800 participants over the age of 55. The research analyzed dietary intake and arterial calcium calcification. Participants who consumed Vitamin K2 experienced a 50% reduction in arterial calcium calcification and a 46% reduction in heart disease mortality. These findings underscore the effectiveness of Vitamin K2 in preventing coronary artery disease.
[Geleijnse, J. M., Vermeer, C., Grobbee, D. E., Schurgers, L. J., Knapen, M. H., van der Meer, I. M., & Hofman, A. (2004). “Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study.” The Journal of Nutrition, 134(11), 3100-3105.].
Vitamin K2 for Cardiovascular Health
Vitamin K2 plays a vital role in cardiovascular health by regulating calcium homeostasis. Its benefits are mediated through the activation of MGP, which prevents calcification in the arteries. Clinical studies consistently demonstrate that Vitamin K2 supplementation can improve cardiovascular health by reducing systemic calcification and arterial stiffness. Embracing Vitamin K2 can lead to healthier hearts and better overall wellness.